Disastrously Wrong

I am reading the book “Back to Virtue” by Peter Kreeft. On page 23, he writes:

The premodern practical philosophy, or life view, flowed from the premodern theoretical philosophy, or world world view: there is a God; therefore conform to him. The modern life view flows from the modern world view: there is no God; therefore we play God to the world. Both philosophies are consistent, but one of the two must be wrong, disastrously wrong.

Which philosophy do you think is “disastrously wrong”?